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Publications scientifiques récentes de chercheurs du Réseau de cellules souches

Forgetting at biologically realistic levels of neurogenesis in alarge-scale hippocampal model.
Tran LM, Josselyn SA, Richards BA, Frankland PW.
Behav Brain Res. 2019 Aug 28. pii: S0166-4328(19)30607-2. doi: 10.1016/j.bbr.2019.112180. [Epub ahead of print]
PMID: 31472193 [PubMed – as supplied by publisher]

Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments.
Shen Y, Grisdale CJ, Islam SA, Bose P, Lever J, Zhao EY, Grinshtein N, Ma Y, Mungall AJ, Moore RA, Lun X, Senger DL, Robbins SM, Wang AY, MacIsaac JL, Kobor MS, Luchman HA, Weiss S, Chan JA, Blough MD, Kaplan DR, Cairncross JG, Marra MA, Jones SJM.
Proc Natl Acad Sci U S A. 2019 Aug 30. pii: 201813495. doi: 10.1073/pnas.1813495116. [Epub ahead of print]
PMID: 31471491 [PubMed – as supplied by publisher]

The ‘serious’ factor in germline modification.
Kleiderman E, Ravitsky V, Knoppers BM.
J Med Ethics. 2019 Aug;45(8):508-513. doi: 10.1136/medethics-2019-105436. Epub 2019 Jul 20.
PMID: 31326898 [PubMed – in process] Free Article

Regulatory and policy tools to address unproven stem cell interventions in Canada: the need for action.
Caulfield T, Murdoch B.
BMC Med Ethics. 2019 Aug 6;20(1):51. doi: 10.1186/s12910-019-0388-4.
PMID: 31383026 [PubMed – in process] Free PMC Article

Using computational fluid dynamics (CFD) modeling to understand murine embryonic stem cell aggregate size and pluripotency distributions in stirred suspension bioreactors.
Borys BS, Le A, Roberts EL, Dang T, Rohani L, Hsu CY, Wyma AA, Rancourt DE, Gates ID, Kallos MS.
J Biotechnol. 2019 Aug 5;304:16-27. doi: 10.1016/j.jbiotec.2019.08.002. [Epub ahead of print]
PMID: 31394111 [PubMed – as supplied by publisher]

TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation.
Campbell SA, McDonald CL, Krentz NAJ, Lynn FC, Hoffman BG.
Cell Rep. 2019 Aug 13;28(7):1830-1844.e6. doi: 10.1016/j.celrep.2019.07.035.
PMID: 31412250 [PubMed – in process] Free Article

The fate and function of oligodendrocyte progenitor cells after traumatic spinal cord injury.
Duncan GJ, Manesh SB, Hilton BJ, Assinck P, Plemel JR, Tetzlaff W.
Glia. 2019 Aug 21. doi: 10.1002/glia.23706. [Epub ahead of print] Review.
PMID: 31433109 [PubMed – as supplied by publisher]

The reduction of XIAP is associated with inflammasome activation in RPE: implications for AMD pathogenesis.
Gao J, Cui JZ, Wang A, Chen HHR, Fong A, Matsubara JA.
J Neuroinflammation. 2019 Aug 22;16(1):171. doi: 10.1186/s12974-019-1558-5.
PMID: 31438981 [PubMed – in process] Free PMC Article
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Local Delivery of Brain-Derived Neurotrophic Factor Enables Behavioral Recovery and Tissue Repair in Stroke-Injured Rats.
Obermeyer JM, Tuladhar A, Payne SL, Ho E, Morshead CM, Shoichet MS.
Tissue Eng Part A. 2019 Aug;25(15-16):1175-1187. doi: 10.1089/ten.TEA.2018.0215. Epub 2019 Feb 27.
PMID: 30612516 [PubMed – in process]

Type 8 long QT syndrome: pathogenic variants in CACNA1C-encoded Cav1.2 cluster in STAC protein binding site.
Mellor GJ, Panwar P, Lee AK, Steinberg C, Hathaway JA, Bartels K, Christian S, Balaji S, Roberts JD, Simpson CS, Boczek NJ, Tester DJ, Radbill AE, Mok NS, Hamilton RM, Kaufman ES, Eugenio PL, Weiss R, January C, McDaniel GM, Leather RA, Erickson C, Falik S, Behr ER, Wilde AAM, Sanatani S, Ackerman MJ, Van Petegem F, Krahn AD, Laksman Z.
Europace. 2019 Aug 13. pii: euz215. doi: 10.1093/europace/euz215. [Epub ahead of print]
PMID: 31408100 [PubMed – as supplied by publisher]
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Clinical trial data sharing: here’s the challenge.
Kochhar S, Knoppers B, Gamble C, Chant A, Koplan J, Humphreys GS.
BMJ Open. 2019 Aug 21;9(8):e032334. doi: 10.1136/bmjopen-2019-032334.
PMID: 31439612 [PubMed – in process] Free Article
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MURC/CAVIN-4 facilitates store-operated calcium entry in neonatal cardiomyocytes.
Malette J, Degrandmaison J, Giguère H, Berthiaume J, Frappier M, Parent JL, Auger-Messier M, Boulay G.
Biochim Biophys Acta Mol Cell Res. 2019 Aug;1866(8):1249-1259. doi: 10.1016/j.bbamcr.2019.03.017. Epub 2019 Apr 2.
PMID: 30951783 [PubMed – in process]

Age- and sex-dependent effects of metformin on neural precursor cells and cognitive recovery in a model of neonatal stroke
Rebecca M. Ruddy, Kelsey V. Adams, and Cindi M. Morshead
Science Advances  11 Sep 2019: Vol. 5, no. 9, eaax1912
DOI: 10.1126/sciadv.aax1912