Publications scientifiques récentes de chercheurs du Réseau de cellules souches

An organ-on-a-chip model for pre-clinical drug evaluation in progressive non-genetic cardiomyopathy.
Wang EY, Kuzmanov U, Smith JB, Dou W, Rafatian N, Lai BFL, Lu RXZ, Wu Q, Yazbeck J, Zhang XO, Sun Y, Gramolini A, Radisic M.
J Mol Cell Cardiol. 2021 Jun 30:S0022-2828(21)00134-6. doi: 10.1016/j.yjmcc.2021.06.012. Online ahead of print.
PMID: 34216608

Investigating inherited arrhythmias using hiPSC-derived cardiomyocytes.
Arslanova A, Shafaattalab S, Lin E, Barszczewski T, Hove-Madsen L, Tibbits GF.
Methods. 2021 Jun 28:S1046-2023(21)00179-1. doi: 10.1016/j.ymeth.2021.06.015. Online ahead of print.
PMID: 34197925

The β Cell in Diabetes: Integrating Biomarkers with Functional Measures.
Kahn SE, Chen YC, Esser N, Taylor AJ, van Raalte DH, Zraika S, Verchere CB.
Endocr Rev. 2021 Jun 28:bnab021. doi: 10.1210/endrev/bnab021. Online ahead of print.
PMID: 34180979

Three decades of genetic privacy: A metaphoric journey.
Knoppers BM, Beauvais MJS.
Hum Mol Genet. 2021 Jun 21:ddab164. doi: 10.1093/hmg/ddab164. Online ahead of print.
PMID: 34155499

The Effects of Biological Sex on Sepsis Treatments in Animal Models: A Systematic Review and a Narrative Elaboration on Sex- and Gender-Dependent Differences in Sepsis.
Zhang M, Montroy J, Sharma R, Fergusson DA, Mendelson AA, Macala KF, Bourque SL, Schlechte JM, Eng MK, McDonald B, Gill SE, Fiest KM, Liaw PC, Fox-Robichaud A, Lalu MM.
Crit Care Explor. 2021 Jun 14;3(6):e0433. doi: 10.1097/CCE.0000000000000433. eCollection 2021 Jun.
PMID: 34151276 Free PMC article. Review.

A defined subset of clonal retinal stem cell spheres is biased to RPE differentiation.
Baakdhah TW, Coles B, van der Kooy D.
iScience. 2021 May 21;24(6):102574. doi: 10.1016/j.isci.2021.102574. eCollection 2021 Jun 25.
PMID: 34151227 Free PMC article.

Atrial-specific hiPSC-derived cardiomyocytes in drug discovery and disease modeling.
Gharanei M, Shafaattalab S, Sangha S, Gunawan M, Laksman Z, Hove-Madsen L, Tibbits GF.
Methods. 2021 Jun 16:S1046-2023(21)00161-4. doi: 10.1016/j.ymeth.2021.06.009. Online ahead of print.
PMID: 34144175

Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo.
Chen ELY, Lee CR, Thompson PK, Wiest DL, Anderson MK, Zúñiga-Pflücker JC.
Cell Rep. 2021 Jun 8;35(10):109227. doi: 10.1016/j.celrep.2021.109227.
PMID: 34107257 Free PMC article.

Consensus International Council for Commonality in Blood Banking Automation-International Society for Cell & Gene Therapy statement on standard nomenclature abbreviations for the tissue of origin of mesenchymal stromal cells.
Viswanathan S, Ciccocioppo R, Galipeau J, Krampera M, Le Blanc K, Martin I, Moniz K, Nolta J, Phinney DG, Shi Y, Szczepiorkowski ZM, Tarte K, Weiss DJ, Ashford P.Cytotherapy. 2021 Jun 8:S1465-3249(21)00644-7. doi: 10.1016/j.jcyt.2021.04.009. Online ahead of print.
PMID: 34116944 Free article.

Designing Hydrogels for 3D Cell Culture Using Dynamic Covalent Crosslinking.
Rizwan M, Baker AEG, Shoichet MS.
Adv Healthc Mater. 2021 Jun;10(12):e2100234. doi: 10.1002/adhm.202100234. Epub 2021 May 14.
PMID: 33987970 Review.

Bioengineering strategies to control epithelial-to-mesenchymal transition for studies of cardiac development and disease.
Bannerman D, Pascual-Gil S, Floryan M, Radisic M.
APL Bioeng. 2021 Apr 23;5(2):021504. doi: 10.1063/5.0033710. eCollection 2021 Jun.
PMID: 33948525 Free PMC article. Review.

Niche-dependent inhibition of neural stem cell proliferation and oligodendrogenesis is mediated by the presence of myelin basic protein.
Lakshman N, Bourget C, Siu R, Bamm VV, Xu W, Harauz G, Morshead CM.
Stem Cells. 2021 Jun;39(6):776-786. doi: 10.1002/stem.3344. Epub 2021 Feb 10.
PMID: 33529418 Free PMC article.

Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice.
Sincennes MC, Brun CE, Lin AYT, Rosembert T, Datzkiw D, Saber J, Ming H, Kawabe YI, Rudnicki MA.
Nat Commun. 2021 May 31;12(1):3253. doi: 10.1038/s41467-021-23577-z.
PMID: 34059674

Lifestyle factors and outcomes in paediatric-onset multiple sclerosis.
Stephens S, Yeh EA.
Lancet Child Adolesc Health. 2021 May 28:S2352-4642(21)00157-7. doi: 10.1016/S2352-4642(21)00157-7. Online ahead of print.
PMID: 34058124 No abstract available.

Maturation of human pluripotent stem cell derived cardiomyocytes in vitro and in vivo.
Gomez-Garcia MJ, Quesnel E, Al-Attar R, Laskary AR, Laflamme MA.
Semin Cell Dev Biol. 2021 May 27:S1084-9521(21)00131-2. doi: 10.1016/j.semcdb.2021.05.022. Online ahead of print.
PMID: 34053865 Review.

Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells.
Funakoshi S, Fernandes I, Mastikhina O, Wilkinson D, Tran T, Dhahri W, Mazine A, Yang D, Burnett B, Lee J, Protze S, Bader GD, Nunes SS, Laflamme M, Keller G.
Nat Commun. 2021 May 26;12(1):3155. doi: 10.1038/s41467-021-23329-z.
PMID: 34039977

De novo revertant fiber formation and therapy testing in a 3D culture model of Duchenne muscular dystrophy skeletal muscle.
Ebrahimi M, Lad H, Fusto A, Tiper Y, Datye A, Nguyen CT, Jacques E, Moyle LA, Nguyen T, Musgrave B, Chávez-Madero C, Bigot A, Chen C, Turner S, Stewart BA, Pegoraro E, Vitiello L, Gilbert PM.
Acta Biomater. 2021 May 25:S1742-7061(21)00330-5. doi: 10.1016/j.actbio.2021.05.020. Online ahead of print.
PMID: 34048976

ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update.
Lovell-Badge R, Anthony E, Barker RA, Bubela T, Brivanlou AH, Carpenter M, Charo RA, Clark A, Clayton E, Cong Y, Daley GQ, Fu J, Fujita M, Greenfield A, Goldman SA, Hill L, Hyun I, Isasi R, Kahn J, Kato K, Kim JS, Kimmelman J, Knoblich JA, Mathews D, Montserrat N, Mosher J, Munsie M, Nakauchi H, Naldini L, Naughton G, Niakan K, Ogbogu U, Pedersen R, Rivron N, Rooke H, Rossant J, Round J, Saitou M, Sipp D, Steffann J, Sugarman J, Surani A, Takahashi J, Tang F, Turner L, Zettler PJ, Zhai X.
Stem Cell Reports. 2021 May 25:S2213-6711(21)00263-0. doi: 10.1016/j.stemcr.2021.05.012. Online ahead of print.
PMID: 34048692 Review.

A finger on the pulse of regeneration: insights into the cellular mechanisms of adult digit tip regeneration.
Storer MA, Miller FD.
Curr Opin Genet Dev. 2021 May 24;70:1-6. doi: 10.1016/j.gde.2021.04.002. Online ahead of print.
PMID: 34044269 Review.

Collagen analogs with phosphorylcholine are inflammation-suppressing scaffolds for corneal regeneration from alkali burns in mini-pigs.
Simpson FC, McTiernan CD, Islam MM, Buznyk O, Lewis PN, Meek KM, Haagdorens M, Audiger C, Lesage S, Gueriot FX, Brunette I, Robert MC, Olsen D, Koivusalo L, Liszka A, Fagerholm P, Gonzalez-Andrades M, Griffith M.
Commun Biol. 2021 May 21;4(1):608. doi: 10.1038/s42003-021-02108-y.
PMID: 34021240

Drawing Inspiration from Developmental Biology for Cardiac Tissue Engineers.
Rafatian N, Vizely K, Al Asafen H, Korolj A, Radisic M.
Adv Biol (Weinh). 2021 May 19:e2000190. doi: 10.1002/adbi.202000190. Online ahead of print.
PMID: 34008910 Review.

Designing Hydrogels for 3D Cell Culture Using Dynamic Covalent Crosslinking.
Rizwan M, Baker AEG, Shoichet MS.
Adv Healthc Mater. 2021 May 14:e2100234. doi: 10.1002/adhm.202100234. Online ahead of print.
PMID: 33987970 Review.

An Optical-Flow-Based Method to Quantify Dynamic Behavior of Human Pluripotent Stem Cell-Derived Cardiomyocytes in Disease Modeling Platforms.
Izadifar M, Berecz T, Apáti Á, Nagy A.
Methods Mol Biol. 2021 May 13. doi: 10.1007/7651_2021_382. Online ahead of print.
PMID: 33982275

The Equitable Implementation of Cystic Fibrosis Personalized Medicines in Canada.
Shemie G, Nguyen MT, Wallenburg J, Ratjen F, Knoppers BM.
J Pers Med. 2021 May 7;11(5):382. doi: 10.3390/jpm11050382.
PMID: 34067090 Review.

Cutting Edge: TCR-β Selection Is Required at the CD4+CD8+ Stage of Human T Cell Development.
Chen ELY, Brauer PM, Martinez EC, Huang X, Yu N, Anderson MK, Li Y, Zúñiga-Pflücker JC.
J Immunol. 2021 May 15;206(10):2271-2276. doi: 10.4049/jimmunol.2100141. Epub 2021 May 3.
PMID: 33941655

Cardiomyocyte-specific Srsf3 deletion reveals a mitochondrial regulatory role.
Dumont AA, Dumont L, Zhou D, Giguère H, Pileggi C, Harper ME, Blondin DP, Scott MS, Auger-Messier M.
FASEB J. 2021 May;35(5):e21544. doi: 10.1096/fj.202002293RR.
PMID: 33819356

Augmented Two-Dimensional Correlation Spectroscopy for the Joint Analysis of Correlated Changes in Spectroscopic and Disparate Sources.
Schulze HG, Rangan S, Vardaki MZ, Iworima DG, Kieffer TJ, Blades MW, Turner RFB, Piret JM.
Appl Spectrosc. 2021 May;75(5):520-530. doi: 10.1177/0003702820979331. Epub 2021 Jan 7.
PMID: 33231477