Recent scientific publications authored by Stem Cell Network researchers

Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice.
Sincennes MC, Brun CE, Lin AYT, Rosembert T, Datzkiw D, Saber J, Ming H, Kawabe YI, Rudnicki MA.
Nat Commun. 2021 May 31;12(1):3253. doi: 10.1038/s41467-021-23577-z.
PMID: 34059674

Lifestyle factors and outcomes in paediatric-onset multiple sclerosis.
Stephens S, Yeh EA.
Lancet Child Adolesc Health. 2021 May 28:S2352-4642(21)00157-7. doi: 10.1016/S2352-4642(21)00157-7. Online ahead of print.
PMID: 34058124 No abstract available.

Maturation of human pluripotent stem cell derived cardiomyocytes in vitro and in vivo.
Gomez-Garcia MJ, Quesnel E, Al-Attar R, Laskary AR, Laflamme MA.
Semin Cell Dev Biol. 2021 May 27:S1084-9521(21)00131-2. doi: 10.1016/j.semcdb.2021.05.022. Online ahead of print.
PMID: 34053865 Review.

Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells.
Funakoshi S, Fernandes I, Mastikhina O, Wilkinson D, Tran T, Dhahri W, Mazine A, Yang D, Burnett B, Lee J, Protze S, Bader GD, Nunes SS, Laflamme M, Keller G.
Nat Commun. 2021 May 26;12(1):3155. doi: 10.1038/s41467-021-23329-z.
PMID: 34039977

De novo revertant fiber formation and therapy testing in a 3D culture model of Duchenne muscular dystrophy skeletal muscle.
Ebrahimi M, Lad H, Fusto A, Tiper Y, Datye A, Nguyen CT, Jacques E, Moyle LA, Nguyen T, Musgrave B, Chávez-Madero C, Bigot A, Chen C, Turner S, Stewart BA, Pegoraro E, Vitiello L, Gilbert PM.
Acta Biomater. 2021 May 25:S1742-7061(21)00330-5. doi: 10.1016/j.actbio.2021.05.020. Online ahead of print.
PMID: 34048976

ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update.
Lovell-Badge R, Anthony E, Barker RA, Bubela T, Brivanlou AH, Carpenter M, Charo RA, Clark A, Clayton E, Cong Y, Daley GQ, Fu J, Fujita M, Greenfield A, Goldman SA, Hill L, Hyun I, Isasi R, Kahn J, Kato K, Kim JS, Kimmelman J, Knoblich JA, Mathews D, Montserrat N, Mosher J, Munsie M, Nakauchi H, Naldini L, Naughton G, Niakan K, Ogbogu U, Pedersen R, Rivron N, Rooke H, Rossant J, Round J, Saitou M, Sipp D, Steffann J, Sugarman J, Surani A, Takahashi J, Tang F, Turner L, Zettler PJ, Zhai X.
Stem Cell Reports. 2021 May 25:S2213-6711(21)00263-0. doi: 10.1016/j.stemcr.2021.05.012. Online ahead of print.
PMID: 34048692 Review.

A finger on the pulse of regeneration: insights into the cellular mechanisms of adult digit tip regeneration.
Storer MA, Miller FD.
Curr Opin Genet Dev. 2021 May 24;70:1-6. doi: 10.1016/j.gde.2021.04.002. Online ahead of print.
PMID: 34044269 Review.

Collagen analogs with phosphorylcholine are inflammation-suppressing scaffolds for corneal regeneration from alkali burns in mini-pigs.
Simpson FC, McTiernan CD, Islam MM, Buznyk O, Lewis PN, Meek KM, Haagdorens M, Audiger C, Lesage S, Gueriot FX, Brunette I, Robert MC, Olsen D, Koivusalo L, Liszka A, Fagerholm P, Gonzalez-Andrades M, Griffith M.
Commun Biol. 2021 May 21;4(1):608. doi: 10.1038/s42003-021-02108-y.
PMID: 34021240

Drawing Inspiration from Developmental Biology for Cardiac Tissue Engineers.
Rafatian N, Vizely K, Al Asafen H, Korolj A, Radisic M.
Adv Biol (Weinh). 2021 May 19:e2000190. doi: 10.1002/adbi.202000190. Online ahead of print.
PMID: 34008910 Review.

Designing Hydrogels for 3D Cell Culture Using Dynamic Covalent Crosslinking.
Rizwan M, Baker AEG, Shoichet MS.
Adv Healthc Mater. 2021 May 14:e2100234. doi: 10.1002/adhm.202100234. Online ahead of print.
PMID: 33987970 Review.

An Optical-Flow-Based Method to Quantify Dynamic Behavior of Human Pluripotent Stem Cell-Derived Cardiomyocytes in Disease Modeling Platforms.
Izadifar M, Berecz T, Apáti Á, Nagy A.
Methods Mol Biol. 2021 May 13. doi: 10.1007/7651_2021_382. Online ahead of print.
PMID: 33982275

The Equitable Implementation of Cystic Fibrosis Personalized Medicines in Canada.
Shemie G, Nguyen MT, Wallenburg J, Ratjen F, Knoppers BM.
J Pers Med. 2021 May 7;11(5):382. doi: 10.3390/jpm11050382.
PMID: 34067090 Review.

Cutting Edge: TCR-β Selection Is Required at the CD4+CD8+ Stage of Human T Cell Development.
Chen ELY, Brauer PM, Martinez EC, Huang X, Yu N, Anderson MK, Li Y, Zúñiga-Pflücker JC.
J Immunol. 2021 May 15;206(10):2271-2276. doi: 10.4049/jimmunol.2100141. Epub 2021 May 3.
PMID: 33941655

Cardiomyocyte-specific Srsf3 deletion reveals a mitochondrial regulatory role.
Dumont AA, Dumont L, Zhou D, Giguère H, Pileggi C, Harper ME, Blondin DP, Scott MS, Auger-Messier M.
FASEB J. 2021 May;35(5):e21544. doi: 10.1096/fj.202002293RR.
PMID: 33819356

Augmented Two-Dimensional Correlation Spectroscopy for the Joint Analysis of Correlated Changes in Spectroscopic and Disparate Sources.
Schulze HG, Rangan S, Vardaki MZ, Iworima DG, Kieffer TJ, Blades MW, Turner RFB, Piret JM.
Appl Spectrosc. 2021 May;75(5):520-530. doi: 10.1177/0003702820979331. Epub 2021 Jan 7.
PMID: 33231477

Pannexin 1 Influences Lineage Specification of Human iPSCs.
Noort RJ, Christopher GA, Esseltine JL.
Front Cell Dev Biol. 2021 Apr 16;9:659397. doi: 10.3389/fcell.2021.659397. eCollection 2021.
PMID: 33937260Free PMC article.

Coming Out to Play: Privacy, Data Protection, Children’s Health, and COVID-19 Research.
Beauvais MJS, Knoppers BM.
Front Genet. 2021 Apr 14;12:659027. doi: 10.3389/fgene.2021.659027. eCollection 2021.
PMID: 33936177Free PMC article.

Induction of stable human FOXP3+ Tregs by a parasite-derived TGF-β mimic.
Cook L, Reid KT, Häkkinen E, de Bie B, Tanaka S, Smyth DJ, White MP, Wong MQ, Huang Q, Gillies JK, Zeigler SF, Maizels RM, Levings MK.
Immunol Cell Biol. 2021 Apr 30. doi: 10.1111/imcb.12475. Online ahead of print.
PMID: 33929751

Empowering Muscle Stem Cells for the Treatment of Duchenne Muscular Dystrophy.
Filippelli RL, Chang NC.
Cells Tissues Organs. 2021 Apr 28:1-14. doi: 10.1159/000514305. Online ahead of print.
PMID: 33910206Review.

In vitro assessment of anti-fibrotic activity does not predict their in vivo efficacy in murine models of Duchenne muscular dystrophy.
Theret M, Low M, Rempel L, Li FF, Tung LW, Contreras O, Chang CK, Wu A, Soliman H, Rossi FMV.
Life Sci. 2021 Apr 20:119482. doi: 10.1016/j.lfs.2021.119482. Online ahead of print.
PMID: 33891939

Peddling promise? An analysis of private umbilical cord blood banking company websites in Canada.
Marcon AR, Murdoch B, Caulfield T.
Cell Tissue Bank. 2021 Apr 23. doi: 10.1007/s10561-021-09919-7. Online ahead of print.
PMID: 33890172

Granulation tissue myofibroblasts during normal and pathological skin healing: The interaction between their secretome and the microenvironment.
Arif S, Attiogbe E, Moulin VJ.
Wound Repair Regen. 2021 Apr 22. doi: 10.1111/wrr.12919. Online ahead of print.
PMID: 33887793

A subpopulation of embryonic microglia respond to maternal stress and influence nearby neural progenitors.
Rosin JM, Sinha S, Biernaskie J, Kurrasch DM.
Dev Cell. 2021 Apr 19:S1534-5807(21)00244-6. doi: 10.1016/j.devcel.2021.03.018. Online ahead of print.
PMID: 33887203

Regulated cell death pathways in doxorubicin-induced cardiotoxicity.
Christidi E, Brunham LR.
Cell Death Dis. 2021 Apr 1;12(4):339. doi: 10.1038/s41419-021-03614-x.
PMID: 33795647Free PMC article.Review.

Compelled Disclosure of Confidential Information in Patient Safety Research.
Du L, Murdoch B, Chiu C, Caulfield T.
J Patient Saf. 2021 Apr 1;17(3):200-206. doi: 10.1097/PTS.0000000000000293.
PMID: 27811589

Gαi-biased apelin analog protects against isoproterenol-induced myocardial dysfunction in rats.
Coquerel D, Delile E, Dumont L, Chagnon F, Murza A, Sainsily X, Salvail D, Sarret P, Marsault E, Auger-Messier M, Lesur O.
Am J Physiol Heart Circ Physiol. 2021 Apr 1;320(4):H1646-H1656. doi: 10.1152/ajpheart.00688.2020. Epub 2021 Feb 26.
PMID: 33635165