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Recent scientific publications authored by Stem Cell Network researchers

JULY
Penetrance of Severe Pulmonary Arterial Hypertension in Response to Vascular Endothelial Growth Factor Receptor 2 Blockade in a Genetically Prone Rat Model Is Reduced by Female Sex.
Chaudhary KR, Deng Y, Yang A, Cober ND, Stewart DJ.
J Am Heart Assoc. 2021 Aug 3;10(15):e019488. doi: 10.1161/JAHA.120.019488. Epub 2021 Jul 28.
PMID: 34315227

Fibroblasts: Origins, definitions, and functions in health and disease.
Plikus MV, Wang X, Sinha S, Forte E, Thompson SM, Herzog EL, Driskell RR, Rosenthal N, Biernaskie J, Horsley V.
Cell. 2021 Jul 22;184(15):3852-3872. doi: 10.1016/j.cell.2021.06.024.
PMID: 34297930 Review.

ISSCR guidelines uphold human right to science for benefit of all.
Master Z, Lovell-Badge R, Knoppers B.
Nature. 2021 Jul;595(7868):494. doi: 10.1038/d41586-021-01959-z.
PMID: 34285410 No abstract available.

Patient engagement in preclinical laboratory research: A scoping review.
Fox G, Fergusson DA, Daham Z, Youssef M, Foster M, Poole E, Sharif A, Richards DP, Hendrick K, Mendelson AA, Macala KF, Monfaredi Z, Montroy J, Fiest KM, Presseau J, Lalu MM.
EBioMedicine. 2021 Jul 16;70:103484. doi: 10.1016/j.ebiom.2021.103484. Online ahead of print.
PMID: 34280783 Free PMC article.

Beyond Polydimethylsiloxane: Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems.
Campbell SB, Wu Q, Yazbeck J, Liu C, Okhovatian S, Radisic M.
ACS Biomater Sci Eng. 2021 Jul 12;7(7):2880-2899. doi: 10.1021/acsbiomaterials.0c00640. Epub 2020 Sep 9.
PMID: 34275293 Review.

The molecular mechanisms of oxygen-sensing in human ductus arteriosus smooth muscle cells: A comprehensive transcriptome profile reveals a central role for mitochondria.
Bentley RET, Hindmarch CCT, Dunham-Snary KJ, Snetsinger B, Mewburn JD, Thébaud A, Lima PDA, Thébaud B, Archer SL.
Genomics. 2021 Jul 8;113(5):3128-3140. doi: 10.1016/j.ygeno.2021.07.006. Online ahead of print.
PMID: 34245829

PNKP is required for maintaining the integrity of progenitor cell populations in adult mice.
Shin W, Alpaugh W, Hallihan LJ, Sinha S, Crowther E, Martin GR, Scheidl-Yee T, Yang X, Yoon G, Goldsmith T, Berger ND, de Almeida LG, Dufour A, Dobrinski I, Weinfeld M, Jirik FR, Biernaskie J.
Life Sci Alliance. 2021 Jul 5;4(9):e202000790. doi: 10.26508/lsa.202000790. Print 2021 Sep.
PMID: 34226276

Drawing Inspiration from Developmental Biology for Cardiac Tissue Engineers.
Rafatian N, Vizely K, Al Asafen H, Korolj A, Radisic M.
Adv Biol (Weinh). 2021 Jul;5(7):e2000190. doi: 10.1002/adbi.202000190. Epub 2021 May 19.
PMID: 34008910 Review.

Granulation tissue myofibroblasts during normal and pathological skin healing: The interaction between their secretome and the microenvironment.
Arif S, Attiogbe E, Moulin VJ.
Wound Repair Regen. 2021 Jul;29(4):563-572. doi: 10.1111/wrr.12919. Epub 2021 Apr 22.
PMID: 33887793

Benefits and obstacles to cell therapy in neonates: The INCuBAToR (Innovative Neonatal Cellular Therapy for Bronchopulmonary Dysplasia: Accelerating Translation of Research).
Thébaud B, Lalu M, Renesme L, van Katwyk S, Presseau J, Thavorn K, Cobey KD, Hutton B, Moher D, Soll RF, Fergusson D.
Stem Cells Transl Med. 2021 Jul;10(7):968-975. doi: 10.1002/sctm.20-0508. Epub 2021 Feb 11.
PMID: 33570257 Free PMC article. Review.

Single Cell Transcriptomics of Ependymal Cells Across Age, Region and Species Reveals Cilia-Related and Metal Ion Regulatory Roles as Major Conserved Ependymal Cell Functions.
MacDonald A, Lu B, Caron M, Caporicci-Dinucci N, Hatrock D, Petrecca K, Bourque G, Stratton JA.
Front Cell Neurosci. 2021 Jul 15;15:703951. doi: 10.3389/fncel.2021.703951. eCollection 2021.
PMID: 34335193 Free PMC article.

 

JUNE
An organ-on-a-chip model for pre-clinical drug evaluation in progressive non-genetic cardiomyopathy.
Wang EY, Kuzmanov U, Smith JB, Dou W, Rafatian N, Lai BFL, Lu RXZ, Wu Q, Yazbeck J, Zhang XO, Sun Y, Gramolini A, Radisic M.
J Mol Cell Cardiol. 2021 Jun 30:S0022-2828(21)00134-6. doi: 10.1016/j.yjmcc.2021.06.012. Online ahead of print.
PMID: 34216608

Investigating inherited arrhythmias using hiPSC-derived cardiomyocytes.
Arslanova A, Shafaattalab S, Lin E, Barszczewski T, Hove-Madsen L, Tibbits GF.
Methods. 2021 Jun 28:S1046-2023(21)00179-1. doi: 10.1016/j.ymeth.2021.06.015. Online ahead of print.
PMID: 34197925

The β Cell in Diabetes: Integrating Biomarkers with Functional Measures.
Kahn SE, Chen YC, Esser N, Taylor AJ, van Raalte DH, Zraika S, Verchere CB.
Endocr Rev. 2021 Jun 28:bnab021. doi: 10.1210/endrev/bnab021. Online ahead of print.
PMID: 34180979

Three decades of genetic privacy: A metaphoric journey.
Knoppers BM, Beauvais MJS.
Hum Mol Genet. 2021 Jun 21:ddab164. doi: 10.1093/hmg/ddab164. Online ahead of print.
PMID: 34155499

The Effects of Biological Sex on Sepsis Treatments in Animal Models: A Systematic Review and a Narrative Elaboration on Sex- and Gender-Dependent Differences in Sepsis.
Zhang M, Montroy J, Sharma R, Fergusson DA, Mendelson AA, Macala KF, Bourque SL, Schlechte JM, Eng MK, McDonald B, Gill SE, Fiest KM, Liaw PC, Fox-Robichaud A, Lalu MM.
Crit Care Explor. 2021 Jun 14;3(6):e0433. doi: 10.1097/CCE.0000000000000433. eCollection 2021 Jun.
PMID: 34151276 Free PMC article. Review.

A defined subset of clonal retinal stem cell spheres is biased to RPE differentiation.
Baakdhah TW, Coles B, van der Kooy D.
iScience. 2021 May 21;24(6):102574. doi: 10.1016/j.isci.2021.102574. eCollection 2021 Jun 25.
PMID: 34151227 Free PMC article.

Atrial-specific hiPSC-derived cardiomyocytes in drug discovery and disease modeling.
Gharanei M, Shafaattalab S, Sangha S, Gunawan M, Laksman Z, Hove-Madsen L, Tibbits GF.
Methods. 2021 Jun 16:S1046-2023(21)00161-4. doi: 10.1016/j.ymeth.2021.06.009. Online ahead of print.
PMID: 34144175

Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo.
Chen ELY, Lee CR, Thompson PK, Wiest DL, Anderson MK, Zúñiga-Pflücker JC.
Cell Rep. 2021 Jun 8;35(10):109227. doi: 10.1016/j.celrep.2021.109227.
PMID: 34107257 Free PMC article.

Consensus International Council for Commonality in Blood Banking Automation-International Society for Cell & Gene Therapy statement on standard nomenclature abbreviations for the tissue of origin of mesenchymal stromal cells.
Viswanathan S, Ciccocioppo R, Galipeau J, Krampera M, Le Blanc K, Martin I, Moniz K, Nolta J, Phinney DG, Shi Y, Szczepiorkowski ZM, Tarte K, Weiss DJ, Ashford P.Cytotherapy. 2021 Jun 8:S1465-3249(21)00644-7. doi: 10.1016/j.jcyt.2021.04.009. Online ahead of print.
PMID: 34116944 Free article.

Designing Hydrogels for 3D Cell Culture Using Dynamic Covalent Crosslinking.
Rizwan M, Baker AEG, Shoichet MS.
Adv Healthc Mater. 2021 Jun;10(12):e2100234. doi: 10.1002/adhm.202100234. Epub 2021 May 14.
PMID: 33987970 Review.

Bioengineering strategies to control epithelial-to-mesenchymal transition for studies of cardiac development and disease.
Bannerman D, Pascual-Gil S, Floryan M, Radisic M.
APL Bioeng. 2021 Apr 23;5(2):021504. doi: 10.1063/5.0033710. eCollection 2021 Jun.
PMID: 33948525 Free PMC article. Review.

Niche-dependent inhibition of neural stem cell proliferation and oligodendrogenesis is mediated by the presence of myelin basic protein.
Lakshman N, Bourget C, Siu R, Bamm VV, Xu W, Harauz G, Morshead CM.
Stem Cells. 2021 Jun;39(6):776-786. doi: 10.1002/stem.3344. Epub 2021 Feb 10.
PMID: 33529418 Free PMC article.