Recent scientific publications authored by Stem Cell Network researchers


Using hiPSC-CMs to Examine Mechanisms of Catecholaminergic Polymorphic Ventricular Tachycardia.
Arslanova A, Shafaattalab S, Ye K, Asghari P, Lin L, Kim B, Roston TM, Hove-Madsen L, Van Petegem F, Sanatani S, Moore E, Lynn F, Søndergaard M, Luo Y, Chen SRW, Tibbits GF.
Curr Protoc. 2021 Dec;1(12):e320. doi: 10.1002/cpz1.320.
PMID: 34958715

Innovation in culture systems to study muscle complexity.
Moyle LA, Davoudi S, Gilbert PM.
Exp Cell Res. 2021 Dec 11;411(1):112966. doi: 10.1016/j.yexcr.2021.112966. Online ahead of print.
PMID: 34906582 Review.

Drug-releasing Microspheres for Stem Cell Differentiation.
Sharma R, Benwood C, Willerth SM.
Curr Protoc. 2021 Dec;1(12):e331. doi: 10.1002/cpz1.331.
PMID: 34919351

Modeling Developmental Brain Diseases Using Human Pluripotent Stem Cells-Derived Brain Organoids – Progress and Perspective.
Bhattacharya A, Choi WWY, Muffat J, Li Y.
J Mol Biol. 2021 Dec 6:167386. doi: 10.1016/j.jmb.2021.167386. Online ahead of print.
PMID: 34883115 Review.

Automated Quantification of Subcellular Particles in Myogenic Progenitors.
Filippelli RL, Omer A, Li S, van Oostende-Triplet C, Gallouzi IE, Chang NC.
Curr Protoc. 2021 Dec;1(12):e325. doi: 10.1002/cpz1.325.
PMID: 34879178

Mechanisms of Arrhythmogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant I79N.
Shafaattalab S, Li AY, Gunawan MG, Kim B, Jayousi F, Maaref Y, Song Z, Weiss JN, Solaro RJ, Qu Z, Tibbits GF.
Front Cell Dev Biol. 2021 Dec 17;9:787581. doi: 10.3389/fcell.2021.787581. eCollection 2021.
PMID: 34977031 Free PMC article.

HLF expression defines the human hematopoietic stem cell state.
Lehnertz B, Chagraoui J, MacRae T, Tomellini E, Corneau S, Mayotte N, Boivin I, Durand A, Gracias D, Sauvageau G.
Blood. 2021 Dec 23;138(25):2642-2654. doi: 10.1182/blood.2021010745.
PMID: 34499717

Implanted pluripotent stem-cell-derived pancreatic endoderm cells secrete glucose-responsive C-peptide in patients with type 1 diabetes.
Ramzy A, Thompson DM, Ward-Hartstonge KA, Ivison S, Cook L, Garcia RV, Loyal J, Kim PTW, Warnock GL, Levings MK, Kieffer TJ.
Cell Stem Cell. 2021 Dec 2;28(12):2047-2061.e5. doi: 10.1016/j.stem.2021.10.003.
PMID: 34861146

Modeling human yolk sac hematopoiesis with pluripotent stem cells.
Atkins MH, Scarfò R, McGrath KE, Yang D, Palis J, Ditadi A, Keller GM.
J Exp Med. 2022 Mar 7;219(3):e20211924. doi: 10.1084/jem.20211924. Epub 2021 Dec 20.
PMID: 34928315

Peddling promise? An analysis of private umbilical cord blood banking company websites in Canada.
Marcon AR, Murdoch B, Caulfield T.
Cell Tissue Bank. 2021 Dec;22(4):609-622. doi: 10.1007/s10561-021-09919-7. Epub 2021 Apr 23.
PMID: 33890172 Free PMC article.

Planar organization of airway epithelial cell morphology using hydrogel grooves during ciliogenesis fails to induce ciliary alignment.
Varma R, Poon J, Liao Z, Aitchison JS, Waddell TK, Karoubi G, McGuigan AP.
Biomater Sci. 2021 Dec 13. doi: 10.1039/d1bm01327k. Online ahead of print.
PMID: 34897300

Temporally Controlled Photouncaged Epidermal Growth Factor Influences Cell Fate in Hydrogels.
Lu YH, Baker AEG, Fokina A, Kufleitner M, Kivijäri T, Shoichet MS.
ACS Biomater Sci Eng. 2021 Dec 3. doi: 10.1021/acsbiomaterials.1c00941. Online ahead of print.
PMID: 34860498

Guided Self-Assembly of ES-Derived Lung Progenitors into Biomimetic Tube Structures That Impact Cell Differentiation.
Soleas JP, Huang L, D’Arcangelo E, Nostro MC, Waddell TK, McGuigan AP, Karoubi G.
Bioengineering (Basel). 2021 Dec 10;8(12):209. doi: 10.3390/bioengineering8120209.
PMID: 34940362 Free PMC article.


Outcomes in newly diagnosed young or high-risk myeloma patients receiving tandem autologous/allogeneic transplant followed by bortezomib maintenance: a phase II study.
LeBlanc R, Ahmad I, Terra R, Boudreault JS, Ogez D, Lamore K, Delisle JS, Bambace N, Bernard L, Cohen S, Kiss T, Lachance S, Landais S, Lemieux-Blanchard É, Sauvageau G, Sebag M, Roy DC, Roy J.
Bone Marrow Transplant. 2021 Nov 29. doi: 10.1038/s41409-021-01532-2. Online ahead of print.
PMID: 34845367

Computational tools for genomic data de-identification: facilitating data protection law compliance.
Bernier A, Liu H, Knoppers BM.
Nat Commun. 2021 Nov 29;12(1):6949. doi: 10.1038/s41467-021-27219-2.
PMID: 34845213 Free PMC article.

Engineering brain and spinal cord tissue constructs.
Modo M, Lampe K, Willerth S.
Brain Res Bull. 2021 Nov 24:S0361-9230(21)00333-6. doi: 10.1016/j.brainresbull.2021.11.012. Online ahead of print.
PMID: 34838643 No abstract available.

Emerging skeletal muscle stromal cell diversity: Functional divergence in fibro/adipogenic progenitor and mural cell populations.
Ritso M, Tung LW, Rossi FMV.
Exp Cell Res. 2021 Nov 22:112947. doi: 10.1016/j.yexcr.2021.112947. Online ahead of print.
PMID: 34822813 Review.

Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19.
Sinha S, Rosin NL, Arora R, Labit E, Jaffer A, Cao L, Farias R, Nguyen AP, de Almeida LGN, Dufour A, Bromley A, McDonald B, Gillrie MR, Fritzler MJ, Yipp BG, Biernaskie J.
Nat Med. 2021 Nov 15. doi: 10.1038/s41591-021-01576-3. Online ahead of print.
PMID: 34782790

Photoreceptor nanotubes mediate the in vivo exchange of intracellular material.
Ortin-Martinez A, Yan NE, Tsai ELS, Comanita L, Gurdita A, Tachibana N, Liu ZC, Lu S, Dolati P, Pokrajac NT, El-Sehemy A, Nickerson PEB, Schuurmans C, Bremner R, Wallace VA.
EMBO J. 2021 Nov 15;40(22):e107264. doi: 10.15252/embj.2020107264. Epub 2021 Sep 8.
PMID: 34494680 Free PMC article.

Cell Therapy with the Cell or Without the Cell for Premature Infants? Time Will Tell.
Thébaud B, Matthay MA.
Am J Respir Crit Care Med. 2021 Nov 9. doi: 10.1164/rccm.202109-2070ED. Online ahead of print.
PMID: 34752727 No abstract available.

Synthesis of an Enzyme-Mediated Reversible Cross-linked Hydrogel for Cell Culture.
Smith KA, Dang M, Baker AEG, Fuehrmann T, Fokina A, Shoichet MS.
Biomacromolecules. 2021 Nov 9. doi: 10.1021/acs.biomac.1c01086. Online ahead of print.
PMID: 34752066

A microfluidic platform enables comprehensive gene expression profiling of mouse retinal stem cells.
Coles BLK, Labib M, Poudineh M, Innes BT, Belair-Hickey J, Gomis S, Wang Z, Bader GD, Sargent EH, Kelley SO, van der Kooy D.
Lab Chip. 2021 Nov 9;21(22):4464-4476. doi: 10.1039/d1lc00790d.
PMID: 34651637

Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models.
Aghazadeh Y, Poon F, Sarangi F, Wong FTM, Khan ST, Sun X, Hatkar R, Cox BJ, Nunes SS, Nostro MC.
Cell Stem Cell. 2021 Nov 4;28(11):1936-1949.e8. doi: 10.1016/j.stem.2021.08.001. Epub 2021 Sep 3.
PMID: 34480863

Induced pluripotency in the context of stem cell expansion bioprocess development, optimization, and manufacturing: a roadmap to the clinic.
Colter J, Murari K, Biernaskie J, Kallos MS.
NPJ Regen Med. 2021 Nov 1;6(1):72. doi: 10.1038/s41536-021-00183-7.
PMID: 34725374 Free PMC article. Review.

An organ-on-a-chip model for pre-clinical drug evaluation in progressive non-genetic cardiomyopathy.
Wang EY, Kuzmanov U, Smith JB, Dou W, Rafatian N, Lai BFL, Lu RXZ, Wu Q, Yazbeck J, Zhang XO, Sun Y, Gramolini A, Radisic M.
J Mol Cell Cardiol. 2021 Nov;160:97-110. doi: 10.1016/j.yjmcc.2021.06.012. Epub 2021 Jun 30.
PMID: 34216608