| Natasha Chang, McGill University, Québec |
Benoit Gentil (McGill University), Michel Tremblay (McGill University), Thomas Durcan (McGill University) |
Restoring muscle stem cell differentiation to enhance regeneration in muscular dystrophy |
$270,000 |
| Nika Shakiba, University of British Columbia, British Columbia |
Michael Kallos (University of Calgary), Sidhartha Goyal (University of Toronto), Li-Fang (Jack), Chu (University of Calgary), Nava Leibovich (National Research Council Canada) |
Bioreactor bottlenecks: selection for aberrant cells in pluripotent stem cell expansion |
$270,000 |
| Michael Laflamme, University Health Network, Ontario |
Bowen Li (University of Toronto), Terrence Yau (University of Toronto) |
RNA-based strategies to promote the engraftment of stem cell-derived cardiomyocytes |
$269,677 |
| Marya Ahmed, University of Alberta |
James Shapiro (University of Alberta), Gregory Korbutt (University of Alberta), Nerea Cuesta Gomez (University of Alberta) |
Stem Cell Cryopreservation Efficacies of Polymeric Nanogels |
$162,000
(jointly funded by Breakthrough T1D at this amount) |
| Kelly McNagny, University of British Columbia, British Columbia |
Peter Zandstra (University of British Columbia), Calvin Roskelley (University of British Columbia), Laura Evgin (BC Cancer) |
Harnessing Stem Cell-Derived Tissue-Resident Innate Lymphoid Cells to Target and Eliminate Solid Tumors |
$270,000 |
| Megan Levings, University of British Columbia, British Columbia |
Bruce Verchere (University of British Columbia), Francis Lynn (University of British Columbia), Peter Zandstra (University of British Columbia) |
Leveraging stem cells to create an engineered model of type 1 diabetes |
$162,000
(jointly funded by Breakthrough T1D at this amount) |
| Lucie Germain, Université Laval, Québec, Québec |
Jason Guertin (Université Laval, Québec), Julie Fradette (Université Laval, Québec), Ma'n Zawati (McGill University), Véronique Moulin (Université Laval, Québec), Elena Pope (The Hospital for Sick Children), Manuel Caruso (Université Laval, Québec), Mélissa Saber (Centre Hospitalier de l'Université de Montréal) |
Toward a combined gene therapy and tissue engineering novel treatment for junctional epidermolysis bullosa |
$270,000 |
| Christian Beausejour, Centre Hospitalier Universitaire Sainte-Justine, Québec |
Anna Jezierski (National Institute of Scientific Research, INRS - Canada), Gerardo Ferbeyre (Centre hospitalier de l'Université de Montréal), Noël Raynal (Université de Montréal) |
Development of improved NK cell therapies for the elimination of senescent cancer cells |
$270,000 |
| Elie Haddad, Centre Hospitalier Universitaire Sainte-Justine, Québec |
Hélène Decaluwe (Centre Hospitalier Universitaire Sainte-Justine), Fabien Touzot (Centre Hospitalier Universitaire Sainte-Justine) |
Harnessing Synthetic Specific Promoters for Targeted Gene Therapy in Hemophagocytic Lymphohistiocytosis (HLH) |
$270,000 |
| May Griffith, CIUSSS de l'Est de l’Ile de Montréal, Québec |
Christos Boutopoulos (CIUSSS de l'Est de l’Ile de Montréal), Denis-Claude Roy (CIUSSS de l'Est de l’Ile de Montréal), Marie-Claude Robert (Université de Montréal) |
Direct Bioprinting for Regenerating the Cornea with Inflammation-Suppressing Bioink |
$269,034 |
| Peter Zandstra, University of British Columbia, British Columbia |
|
Automating Systems Biology and Machine Learning for Multiscale Regulatory Network Discovery in Stem Cell Differentiation |
$270,000 |
| Corinne Hoesli, McGill University, Québec |
Andras Nagy (Mount Sinai Hospital), André Bégin-Drolet (Université Laval, Québec), Richard Leask (McGill University), Steven Paraskevas (The Research Institute of the McGill University Health Centre), Jean Ruel (Université Laval, Québec), Timothy Kieffer (University of British Columbia) |
Vascular lattice bioartificial pancreas for diabetes cellular therapy |
$162,000
(jointly funded by Breakthrough T1D at this amount) |
| Fabio Rossi, University of British Columbia, British Columbia |
|
Engineering hPS derived myogenic progenitors to deliver anti-fibrotic molecules |
$270,000 |
| Cheryle Seguin, Western University, Ontario |
Brian Amsden (Queen's University), Lauren Flynn (Western University), Dmitriy Sheyn (Cedars-Sinai Medical Center) |
Delivery of induced pluripotent stem cells in cell-instructive composite hydrogels for nucleus pulposus regeneration |
$270,000 |
