Discover the science conducted by stem cell and RM researchers

NOVEMBER

Donation and transplantation coverage in the Canadian media: a content analysis of story focus over 2 decades. 
Marcon AR, Caulfield T.
Can J Surg. 2022 Oct 12;65(5):E661-E664. doi: 10.1503/cjs.012721. Print 2022 Sep-Oct.
PMID: 36223934 Free PMC article.

Numb regulates Tau levels and prevents neurodegeneration in tauopathy mouse models. 
Lacomme M, Hales SC, Brown TW, Stevanovic K, Jolicoeur C, Cai J, Bois T, Desrosiers M, Dalkara D, Cayouette M.
Sci Adv. 2022 Oct 21;8(42):eabm4295. doi: 10.1126/sciadv.abm4295. Epub 2022 Oct 19.
PMID: 36260685 Free PMC article.

TNFα and IFNγ cooperate for efficient pro- to anti-inflammatory transition of macrophages during muscle regeneration. 
Babaeijandaghi F, Paiero A, Long R, Tung LW, Smith SP, Cheng R, Smandych J, Kajabadi N, Chang CK, Ghassemi A, Kennedy WDM, Soliman H, Schutz PW, Rossi FMV.
Proc Natl Acad Sci U S A. 2022 Nov;119(44):e2209976119. doi: 10.1073/pnas.2209976119. Epub 2022 Oct 24.
PMID: 36279473

Probing the effects of matrix-derived microcarrier composition on human adipose-derived stromal cells cultured dynamically within spinner flask bioreactors. 
Kornmuller A, Cooper TT, Jani A, Lajoie GA, Flynn LE.
J Biomed Mater Res A. 2022 Oct 10. doi: 10.1002/jbm.a.37459. Online ahead of print.
PMID: 36210786

Impact of Implementing a Bendamustine-based Conditioning Regimen on outcomes of Autologous Stem Cell Transplant in Lymphoma while Novel Cellular Therapies Emerge. 
Lachance S, Bourguignon A, Boisjoly JA, Bouchard P, Ahmad I, Bambace N, Bernard L, Cohen S, Delisle JS, Fleury I, Kiss T, Mollica L, Roy DC, Sauvageau G, Veilleux O, Zehr J, Chagnon M, Roy J.
Transplant Cell Ther. 2022 Oct 12:S2666-6367(22)01698-0. doi: 10.1016/j.jtct.2022.10.003. Online ahead of print.
PMID: 36243319

Impact of Exosomes Released by Different Corneal Cell Types on the Wound Healing Properties of Human Corneal Epithelial Cells. 
Desjardins P, Berthiaume R, Couture C, Le-Bel G, Roy V, Gros-Louis F, Moulin VJ, Proulx S, Chemtob S, Germain L, Guérin SL.
Int J Mol Sci. 2022 Oct 13;23(20):12201. doi: 10.3390/ijms232012201.
PMID: 36293057 Free PMC article.

Affibody-mediated controlled release of fibroblast growth factor 2. 
Bostock C, Teal CJ, Dang M, Golinski AW, Hackel BJ, Shoichet MS.
J Control Release. 2022 Oct;350:815-828. doi: 10.1016/j.jconrel.2022.09.004. Epub 2022 Sep 13.
PMID: 36087800

Returning individual research results in international direct-to-participant genomic research: results from a 31-country study. 
Lang M, Zawati MH.
Eur J Hum Genet. 2022 Oct;30(10):1132-1137. doi: 10.1038/s41431-022-01103-z. Epub 2022 Apr 28.
PMID: 35478220 Free PMC article.

An Engineered Paper-Based 3D Co-Culture Model of Pancreatic Cancer to Study the Impact of Tissue Architecture and Microenvironmental Gradients on Cell Phenotype.
Cadavid JL, Latour S, Nowlan F, Co IL, Landon-Brace N, Wouters BG, Grünwald BT, Nitz M, Jackson H, McGuigan AP.Adv Healthc Mater. 2022 Oct 29:e2201846. doi: 10.1002/adhm.202201846. Online ahead of print.
PMID: 36308030

OCTOBER

Modeling human multi-lineage heart field development with pluripotent stem cells.
Yang D, Gomez-Garcia J, Funakoshi S, Tran T, Fernandes I, Bader GD, Laflamme MA, Keller GM.
Cell Stem Cell. 2022 Sep 1;29(9):1382-1401.e8. doi: 10.1016/j.stem.2022.08.007.
PMID: 36055193

Calcium-dependent transcriptional changes in human pancreatic islet cells reveal functional diversity in islet cell subtypes. 
Yoon JS, Sasaki S, Velghe J, Lee MYY, Winata H, Nian C, Lynn FC.
Diabetologia. 2022 Sep;65(9):1519-1533. doi: 10.1007/s00125-022-05718-1. Epub 2022 May 26.
PMID: 35616696 Free PMC article.

Viscoelastic Notch Signaling Hydrogel Induces Liver Bile Duct Organoid Growth and Morphogenesis.
Rizwan M, Ling C, Guo C, Liu T, Jiang JX, Bear CE, Ogawa S, Shoichet MS.
Adv Healthc Mater. 2022 Sep 30:e2200880. doi: 10.1002/adhm.202200880. Online ahead of print.
PMID: 36180392

Modulating Myogenesis: An Optimized In Vitro Assay to Pharmacologically Influence Primary Myoblast Differentiation. 
VanGenderen CA, Granet JA, Filippelli RL, Liu Y, Chang NC.
Curr Protoc. 2022 Sep;2(9):e565. doi: 10.1002/cpz1.565.
PMID: 36165685

Carm1 and the Epigenetic Control of Stem Cell Function. 
Saber J, Rudnicki MA.
Stem Cells Transl Med. 2022 Sep 14:szac068. doi: 10.1093/stcltm/szac068. Online ahead of print.
PMID: 36103286

Mutations in BCOR, a co-repressor of CRX/OTX2, are associated with early-onset retinal degeneration. 
Langouët M, Jolicoeur C, Javed A, Mattar P, Gearhart MD, Daiger SP, Bertelsen M, Tranebjærg L, Rendtorff ND, Grønskov K, Jespersgaard C, Chen R, Sun Z, Li H, Alirezaie N, Majewski J, Bardwell VJ, Sui R, Koenekoop RK, Cayouette M.
Sci Adv. 2022 Sep 9;8(36):eabh2868. doi: 10.1126/sciadv.abh2868. Epub 2022 Sep 7.
PMID: 36070393 Free PMC article.

Facile Fabrication of Injectable Alginate and Poly (3,4-ethylenedioxythiophene) Based Soft Electrodes Towards the Goal of Neuro-regenerative Applications. 
Perkucin I, Lau KSK, Chen T, Iwasa SN, Naguib HE, Morshead CM.
Adv Healthc Mater. 2022 Sep 30:e2201164. doi: 10.1002/adhm.202201164. Online ahead of print.
PMID: 36177684

A century long journey from the discovery of insulin to the implantation of stem cell derived islets. 
Ramzy A, Belmonte PJ, Braam MJS, Ida S, Wilts EM, Levings MK, Rezania A, Kieffer TJ.
Endocr Rev. 2022 Sep 16:bnac021. doi: 10.1210/endrev/bnac021. Online ahead of print.
PMID: 36111962

Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis. 
Lithopoulos MA, Toussay X, Zhong S, Xu L, Mustafa SB, Ouellette J, Freitas-Andrade M, Comin CC, Bassam HA, Baker AN, Sun Y, Wakem M, Moreira AG, Blanco CL, Vadivel A, Tsilfidis C, Seidner SR, Slack RS, Lagace DC, Wang J, Lacoste B, Thébaud B.
J Clin Invest. 2022 Sep 22:e146095. doi: 10.1172/JCI146095. Online ahead of print.
PMID: 36136598

The impact of patient engagement on trials and trialists in Ontario, Canada: An interview study with IMPACT awardees. 
Nicholls SG, Fox G, Monfaredi Z, Poole E, Garritty C, Maybee A, Presseau J, Shea B, Fergusson DA.
Res Involv Engagem. 2022 Sep 7;8(1):50. doi: 10.1186/s40900-022-00381-7.
PMID: 36071496 Free PMC article.

High Throughput Omnidirectional Printing of Tubular Microstructures from Elastomeric Polymers. 
Liu C, Campbell SB, Li J, Bannerman D, Pascual-Gil S, Kieda J, Wu Q, Herman PR, Radisic M.
Adv Healthc Mater. 2022 Sep 27:e2201346. doi: 10.1002/adhm.202201346. Online ahead of print.
PMID: 36165232

Peering into the dark corners of knowledge synthesis to understand the influence of predatory journals on systematic reviews. 
Lalu MM, Albert MA, Cobey KD.
J Clin Epidemiol. 2022 Sep 14:S0895-4356(22)00226-8. doi: 10.1016/j.jclinepi.2022.09.005. Online ahead of print.
PMID: 36115546 No abstract available.