Découvrez les recherches menées actuellement dans le domaine des cellules souches et de la MR

Les publications scientifiques sont présentées dans la langue dans laquelle elles ont été soumises.

AVRIL

Efficient Isolation and Ex Vivo Differentiation of Murine Satellite Cells from Healthy and Dystrophic Muscle. Cusmano AA, VanGenderen CA, Lorenz TO, Yang Y, Chang NC. Methods Mol Biol. 2025 Mar 22. doi: 10.1007/7651_2025_608. Online ahead of print. PMID: 40117021

Redesigned chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in vitro and in vivo in the stroke-injured rat brain. Letko Khait N, Zuccaro S, Abdo D, Cui H, Siu R, Ho E, Morshead CM, Shoichet MS. Biomaterials. 2025 Mar;314:122818. doi: 10.1016/j.biomaterials.2024.122818. Epub 2024 Sep 7. PMID: 39260032

Clonal lineage tracing and transcriptomics of cortical progenitor populations reveal maintenance of differentiation potential. Harkins D, Ali S, Tockovska T, Ciganovic S, Casasbuenas DL, Watanabe S, Ouzikov S, Yuzwa SA. Stem Cell Reports. 2025 Mar 11;20(3):102418. doi: 10.1016/j.stemcr.2025.102418. Epub 2025 Feb 13. PMID: 39952245

Brain pericytes and perivascular fibroblasts are stromal progenitors with dual functions in cerebrovascular regeneration after stroke. Bernier LP, Hefendehl JK, Scott RW, Tung LW, Lewis CA, Soliman H, Simm S, Dissing-Olesen L, Hofmann J, Guo D, DeMeglio M, Rossi FM, Underhill TM, MacVicar BA. Nat Neurosci. 2025 Mar;28(3):517-535. doi: 10.1038/s41593-025-01872-y. Epub 2025 Feb 17. PMID: 39962273

Dissecting cardiovascular disease-associated noncoding genetic variants using human iPSC models. Dababneh SF, Babini H, Jiménez-Sábado V, Teves SS, Kim KH, Tibbits GF. Stem Cell Reports. 2025 Mar 11:102467. doi: 10.1016/j.stemcr.2025.102467. Online ahead of print. PMID: 40118058 Review.

mTORC1 and mTORC2 synergy in human neural development, disease, and regeneration. Dhaliwal NK, Muffat J, Li Y. Neural Regen Res. 2025 Mar 25. doi: 10.4103/NRR.NRR-D-24-00961. Online ahead of print. PMID: 40146001 No abstract available.

The changing landscape of nonobstructive azoospermia. Garabed LR, Flannigan R. Curr Opin Urol. 2025 Mar 1;35(2):127-134. doi: 10.1097/MOU.0000000000001252. Epub 2024 Nov 27. PMID: 39604250 Review.

Recent advances in 3D bioprinted neural models: A systematic review on the applications to drug discovery. Orr A, Kalantarnia F, Nazir S, Bolandi B, Alderson D, O’Grady K, Hoorfar M, Julian LM, Willerth SM. Adv Drug Deliv Rev. 2025 Mar;218:115524. doi: 10.1016/j.addr.2025.115524. Epub 2025 Feb 1. PMID: 39900293 Review.

Recent Advances in Modeling Tissues Using 3D Bioprinted Nanocellulose Bioinks. Walters-Shumka JP, Cheng C, Jiang F, Willerth SM. ACS Biomater Sci Eng. 2025 Mar 10. doi: 10.1021/acsbiomaterials.4c01902. Online ahead of print. PMID: 40065192 Review.

Using Three-Dimensional Bioprinting to Generate Realistic Models of Wound Healing. Díaz GY, da Silva VA, Kalantarnia F, Scheck K, Tschofen SA, Tuffs SW, Willerth SM. Adv Wound Care (New Rochelle). 2025 Mar 5. doi: 10.1089/wound.2024.0138. Online ahead of print. PMID: 40040420 Review.

Synthesis and characterization of photo-cross-linkable quince seed-based hydrogels for soft tissue engineering applications. Jafari A, Bhatt K, Niknezhad SV, Ajji A, Griffith M, Andelfinger G, Bencherif SA, Savoji H. Carbohydr Polym. 2025 Mar 15;352:123140. doi: 10.1016/j.carbpol.2024.123140. Epub 2024 Dec 12. PMID: 39843050

Transforming Drug Discovery with Miniaturized Predictive Tissue Models. Akbari M. Micromachines (Basel). 2025 Mar 3;16(3):299. doi: 10.3390/mi16030299. PMID: 40141910 Free PMC article.

MARS

Optimizing Electrical Field Stimulation Parameters Reveals the Maximum Contractile Function of Human Skeletal Muscle Microtissues. Tiper Y, Xie Z, Hofemeier AD, Lad H, Luber M, Krawetz R, Betz T, Zimmermann WH, Morton AB, Segal SS, Gilbert PM. Am J Physiol Cell Physiol. 2025 Feb 28. doi: 10.1152/ajpcell.00308.2024. Online ahead of print.PMID: 40019026

Intrinsic Muscle Stem Cell Dysfunction Contributes to Impaired Regeneration in the mdx Mouse. Esper ME, Brun CE, Lin AYT, Feige P, Catenacci MJ, Sincennes MC, Ritso M, Rudnicki MA. J Cachexia Sarcopenia Muscle. 2025 Feb;16(1):e13682. doi: 10.1002/jcsm.13682. PMID: 39723578 Free PMC article.

Delphi-driven consensus definition for mesenchymal stromal cells and clinical reporting guidelines for mesenchymal stromal cell-based therapeutics. Renesme L, Cobey KD, Lalu MM, Bubela T, Chinnadurai R, De Vos J, Dunbar R, Fergusson D, Freund D, Galipeau J, Horwitz E, Lê M, Matthay M, Moher D, Nolta J, Parker G, Phinney DG, Rao M, Rasko JEJ, Rocco PRM, Rossi F, Myles MR, Viswanathan S, Thébaud B. Cytotherapy. 2025 Feb;27(2):146-168. doi: 10.1016/j.jcyt.2024.10.008. Epub 2024 Oct 29. PMID: 39580717

3D Bioprinted Coaxial Testis Model Using Human Induced Pluripotent Stem Cells:A Step Toward Bicompartmental Cytoarchitecture and Functionalization. Robinson MA, Kung SH, Youssef KY, Scheck KM, Bell RH, Sar F, Haegert AM, Asmae MM, Cheng C, Yeack SV, Mathur BT, Jiang F, Collins CC, Hach F, Willerth SM, Flannigan RK. Adv Healthc Mater. 2025 Feb 16:e2402606. doi: 10.1002/adhm.202402606. Online ahead of print. PMID: 39955738

Timing neural development and regeneration. Blackshaw S, Cayouette M. Curr Opin Neurobiol. 2025 Feb 25;91:102976. doi: 10.1016/j.conb.2025.102976. Online ahead of print. PMID: 40010202 Review.

Assessment of immune modulation strategies to enhance survival and integration of human neural progenitor cells in rodent models of spinal cord injury. Lou Z, Post A, Nagoshi N, Hong J, Hejrati N, Chio JCT, Khazaei M, Fehlings MG. Stem Cells Transl Med. 2025 Feb 11;14(2):szae090. doi: 10.1093/stcltm/szae090. PMID: 39931999 Free PMC article. Review.

Effect of Fibroblast Growth Factor-2 on Melanocyte Proliferation in Tissue-Engineered Skin Substitutes. Ferland K, Magne B, De Koninck H, Barbier MA, Larouche D, Germain L. Int J Mol Sci. 2025 Feb 17;26(4):1704. doi: 10.3390/ijms26041704. PMID: 40004167 Free PMC article.

3D Bioprinted Coaxial Testis Model Using Human Induced Pluripotent Stem Cells:A Step Toward Bicompartmental Cytoarchitecture and Functionalization. Robinson MA, Kung SH, Youssef KY, Scheck KM, Bell RH, Sar F, Haegert AM, Asmae MM, Cheng C, Yeack SV, Mathur BT, Jiang F, Collins CC, Hach F, Willerth SM, Flannigan RK. Adv Healthc Mater. 2025 Feb 16:e2402606. doi: 10.1002/adhm.202402606. Online ahead of print. PMID: 39955738

Recent advances in 3D bioprinted neural models: A systematic review on the applications to drug discovery. Orr A, Kalantarnia F, Nazir S, Bolandi B, Alderson D, O’Grady K, Hoorfar M, Julian LM, Willerth SM. Adv Drug Deliv Rev. 2025 Mar;218:115524. doi: 10.1016/j.addr.2025.115524. Epub 2025 Feb 1. PMID: 39900293 Review.

Bioprinting-By-Design of Hydrogel-Based Biomaterials for In Situ Skin Tissue Engineering. Douglas A, Chen Y, Elloso M, Levschuk A, Jeschke MG. Gels. 2025 Feb 3;11(2):110. doi: 10.3390/gels11020110. PMID: 39996653 Free PMC article. Review.

Brain pericytes and perivascular fibroblasts are stromal progenitors with dual functions in cerebrovascular regeneration after stroke. Bernier LP, Hefendehl JK, Scott RW, Tung LW, Lewis CA, Soliman H, Simm S, Dissing-Olesen L, Hofmann J, Guo D, DeMeglio M, Rossi FM, Underhill TM, MacVicar BA. Nat Neurosci. 2025 Feb 17. doi: 10.1038/s41593-025-01872-y. Online ahead of print. PMID: 39962273

Identification of a Therapeutic Window for Neurovascular Unit Repair after Experimental Spinal Cord Injury. Hubertus V, Meyer L, Waldmann L, Roolfs L, Taheri N, Kersting K, von Bronewski E, Nieminen-Kelhä M, Kremenetskaia I, Uhl C, Fiedler KC, Ode JE, Rex A, Prüß H, Rakhymzhan A, Hauser AE, Niesner R, Heppner FL, Fehlings MG, Vajkoczy P. J Neurotrauma. 2025 Feb;42(3-4):212-228. doi: 10.1089/neu.2024.0233. Epub 2024 Nov 26. PMID: 39585767