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Résultats des concours de financement de 2018-19 du RCS : essais cliniques

Chercheur principalCochercheursTitre du projetFonds du RCS
Jean Roy – Hôpital
Maisonneuve-
Rosemont (HMR)
Guy Sauvageau (UdeM), Jean-Sebastien Delisle (HMR), Richard Leblanc (HMR), Sandra Cohen (HMR), Silvy Lachance (HMR), Imran Ahmad (HMR), Émilie Lemieux-Blanchard (CRCHUM), Michael Sebag (MUHC), Sebastien Lemieux (UdeM), Gabriel Tremblay (Geneconomic)Allogeneic stem cell transplant using UM171 expanded cord bloods for patients with high-risk multiple myeloma500 000 $
James Shapiro – U of APeter Senior (U of A), Peter Light (U of A), Gregory Korbutt (U of A), Eugene Brandon (Viacyte Inc.), Kevin D’Amour (Viacyte Inc.), Howard Foyt (Viacyte Inc.), Sylvain Bedard (CEPPP), Bart Roep (U Leiden), Joanna Preston (TEC Edmonton), Chris McCabe (U of A)Pancreatic Progenitor Cell Therapy: Solving Supply and Survival Issues of Islet Cell Transplantation for T1DM500 000 $
Duncan Stewart – OHRIDavid Courtman (GMP Facility OHRI), Michael Kutryk (SMH), Chris Glover (UOHI), Hung-Ly Quoc (MHI), Alexander Dick (UOHI), Michel Lemay (UOHI), Kim Connelly (SMH), Howard Leong Poi (SMH), Josep Rodes-Cabau (U Laval), Dominique Joyal (JGH)Enhanced Angiogenic Cell Therapy for Acute Myocardial Infarction (ENACT-AMI)500 000 $

Sommaire pour le programme des essais cliniques

Demandes reçuesDemandes dont l’acceptation est recommandéePourcentage d’acceptation des demandesInvestissement total
4375%1,5 M$

Résultats des concours de financement de 2018-19 du RCS : programme d’équipes de recherche sur les maladies

Chercheur principalCochercheursTitre du projetFonds du RCS
Gilbert Bernier – Hôpital
Maisonneuve-
Rosemont (HMR)
May Griffith (UdeM), Jean-Francois Bouchard (UdeM), Flavio Rezende (HMR), Cynthia Qian (UdeM), Mario Filion (INRS)Macula transplantation for the treatment of retinal degenerative diseases200 000 $
Joanna Matsubara – UBCMarinko Sarunic (SFU), David Maberly (UBC), Orson Moritz (UBC), Arif Samad (DU), Sean Lumb (UBC)Treating advanced retinal degeneration – rebuilding multiple co-dependent retinal layers with stem cells100 000 $
Lauralyn McIntyre – OHRIShirley Mei (OHRI), Duncan Stewart (OHRI), Dean Fergusson (OHRI), John Marshall (SMH), Keith Walley (UBC), Claudia dos Santos (SMH), Brent Winston (U of C), Shane English (OHRI), Alexis Turgeon (U Laval), Geeta Mehta (U of T), Robert Green (DU), Alison Fox-Robichaud (Hamilton Health Sciences Corporation), Margaret Herridge (UHN), John Granton (U of T), Paul Hebert (CRCHUM), Kednapa Thavorn (OHRI), Timothy Ramsay (OHRI), David Courtman (GMP Facility OHRI), Dana Devine (CBS)Cellular Immunotherapy for Septic Shock (CISS2): A Phase II Multicentre Clinical Trial200 000 $
Freda Miller – Hospital for Sick Children (HSC)Donald Mabbott (HSC), David Kaplan (HSC), Cindi Morshead (U of T), Jing Wang (OHRI), Ann Yeh (HSC), Douglas Munoz (Queens U), Paul Frankland (HSC), Wolfram Tetzlaff (UBC), Brian Nieman (HSC)Pharmacological recruitment of endogenous neural precursors to promote pediatric white matter repair200 000 $
Massimiliano Paganelli – CHU Sainte-Justine, UdeMElie Haddad (UdeM), Christian Beausejour (UdeM), Ariella Shikanov (U of Michigan), Serge McGraw (UdeM), Yves Théoret (CHU Sainte-Justine), Michel Lallier (CHU Sainte-Justine)

Safety and efficacy of stem cell-derived encapsulated liver tissue to treat liver failure without immunosuppression100 000 $
James Shapiro – U of AGregory Korbutt (U of A), ViaCyte Inc., Joanna Preston (TEC Edmonton), Peter Senior (U of A), Bruce Verchere (UBC)Development of a novel stem cell-derived transplant modality for type 1 diabetes100 000 $
Bruce Verchere – UBCFrancis Lynn (UBC), Megan Levings (UBC), Tim Kieffer (UBC), Dina Panagiotopoulos (UBC), Brad Hoffman (UBC), Garth Warnock (UBC), Gregory Korbutt (UofA)Genetic manipulation of hES-derived insulin-producing cells to improve graft outcomes200 000 $

Sommaire pour le programme des équipes de recherche sur les maladies

Demandes reçuesDemandes dont l’acceptation est recommandéePourcentage d’acceptation des demandesInvestissement total
11764%1,1 M$

Résultats des concours de financement de 2018-19 du RCS : programme de recherches d’impact

ChercheurAxe de rechercheTitre du projetFonds du RCS
Florian Bentzinger – UdeSherbrooke
(Principal Investigator)

Eric Marsault (UdeSherbrooke), Mannix Auger-Messier (UdeSherbrooke), Nicolas Dumont (CHU-Sainte-Justine, UdeM), Frederic Balg (UdeSherbrooke)
Transfert des découvertesApelinergic Compounds for the treatment of muscular dystrophy99 000 $
Mick Bhatia – McMaster
(Principal Investigator)

Rima Al-Awar (OICR)
Transfert des découvertesIdentification of kinases and their target substrates in early human PSC specification100 000 $
Timothy Caulfield – U of A
(Principal Investigator)

Amy Zarzeczny (UofR), Barbara von Tigerstrom (UofA), Tania Bubela (SFU), Yann Joly (McGill), Zubin Master (Mayo Clinic), Jeremy Snyder (SFU), Ubaka Ogbogu (UofA)
Politique publiqueThe Next Step: Specific Strategies for Addressing the Marketing of Unproven Stem Cell Therapies40 000 $
Nicolas Dumont – CHU Sainte-Justine, UdeM (Principal Investigator)

Sylvie Girard (UdeM), Cam-Tu Nguyen (UdeM), Phillipe Campeau (UdeM), Christian Beauséjour (UdeM)
Transfert des découvertesTargeting muscle stem cells to mitigate Duchenne muscular dystrophy100 000 $
John Hassell – McMaster
(Principal Investigator)

Rima Al-awar (OICR)
Transfert des découvertesHTR5A as a target for anticancer stem cell drug discovery99 500 $
Timothy Kieffer – UBC
(Principal Investigator)

Ali Rezania (Viacyte Inc.)
Application et accélérateur cliniquesAssessment of Cell Maturation and Function in Subcutaneous Macroencapsulation Devices in Rodents100 000 $
Bartha Knoppers – McGill
(Principal Investigator)

Rosario Isai (OHRI), Tim Caulfield (UofA), Amy Zarzeczny (UofR), Tania Bubela (SFU), Ubaka Ogbogu (UofA), Vardit Ravitsky (UdeM)
Politique publiqueReforming Canadian Stem Cell Policy: Moving Beyond the Assisted Human Reproduction Act (AHRA)39 736 $
Zachary Laksman – UBC
(Principal Investigator)

Glen Tibbits (SFU)
Application et accélérateur cliniquesUsing stem cells to test new drugs for atrial fibrillation100 000 $
Lauralyn McIntyre – OHRI
(Principal Investigator)

Shirley Mei (OHRI), Duncan Stewart (OHRI), Dean Fergusson (OHRI), John Marshall (SMH), Keith Walley (UBC), Claudia dos Santos (SMH), Brent Winston (U of C), Shane English (OHRI), Alexis Turgeon (U Laval), Geeta Mehta (U of T), Robert Green (DU), Alison Fox-Robichaud (McMaster), Margaret Herridge (U of T), John Granton (U of T), Paul Hebert (CRCHUM), Kednapa Thavorn (OHRI), Timothy Ramsay (OHRI), David Courtman (GMP Facility OHRI)
Application et accélérateur cliniquesCellular Immunotherapy for Septic Shock (CISS2): A Phase II Multicentre Clinical Trial100 000 $
Derrick Rancourt – UC
(Principal Investigator)

Eric Jervis (STEMCELL Technologies)
CommercialisationEnhancing the Efficiency of Genome Engineering in Human Pluripotent Stem Cells100 000 $
Bernard Thébaud – OHRI
(Principal Investigator)

Mervin Yoder (Hospital for Children, Indianapolis), Dylan Burger (U of O)
Application et accélérateur cliniquesEndothelial Progenitor Cell-derived Therapies for Neonatal Pulmonary Hypertension99 905 $
Glen Tibbits – SFU
(Principal Investigator)

Thomas Claydon (SFU), Zachary Laksman (UBC), Shubhayan Sanatani (UBC)
Application et accélérateur cliniquesDeveloping an hiPSC-CM based protocol to investigate SIDS-implicated sudden cardiac arrest in infants99 500 $
Eve Tsai – OHRI
(Principal Investigator)

Xudong Cao (U of O), Ruth Slack (U of O)
Application et accélérateur cliniquesTranslating an animal endogenous stem/progenitor cell repair strategy for stroke to humans100 000 $
Peter Zandstra – UBC
(Principal Investigator)

Fiona Watt (King’s College, London, UK), Davide Danovi (King’s College, London, UK)
CommercialisationA robust, quantitative, and high-throughput assay to rapidly characterize human induced pluripotent stem cells100 000 $

Sommaire du programme de recherche d’impact

Demandes reçuesDemandes dont l’acceptation recommandéePourcentage d’acceptation des demandesInvestissement total
461430%1,4 M$

* Les titres des projets sont affichés selon la langue de soumission

Résultats des concours de financement de 2016 du RCS

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