Découvrez les recherches menées actuellement dans le domaine des cellules souches et de la MR

Les publications scientifiques sont présentées dans la langue dans laquelle elles ont été soumises.

OCTOBRE

Making Advanced Therapies Affordable and Accessible: Two Strategic Approaches. Ogbogu U, Albrecht L.Dev World Bioeth. 2025 Sep 10. doi: 10.1111/dewb.70004. Online ahead of print.PMID: 40928580

High-throughput bioprinting to produce micropatterned neuroepithelial tissues and model TSC2-deficient brain malformations. Imani Farahani N, Wong KKL, Allen G, Minhas A, Lin L, Nazir S, Julian LM.Cell Rep Methods. 2025 Sep 17:101177. doi: 10.1016/j.crmeth.2025.101177. Online ahead of print.PMID: 40967207 Free article.

Scale-down optimization of a robust, parallelizable human induced pluripotent stem cell bioprocess for high-throughput research. Colter J, Dang T, Malinovska J, Corpuz JM, Modrcin D, Krawetz R, Murari K, Kallos MS.Biotechnol Rep (Amst). 2025 May 22;47:e00900. doi: 10.1016/j.btre.2025.e00900. eCollection 2025 Sep.PMID: 40521435 Free PMC article.

Augmenting AMPA receptor signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery. Hachem LD, Moradi Chameh H, Balbinot G, Mothe AJ, Pacis A, Geng Li RT, Valiante TA, Lu W, Tator CH, Fehlings MG.Nat Neurosci. 2025 Oct;28(10):2054-2066. doi: 10.1038/s41593-025-02044-8. Epub 2025 Sep 15.PMID: 40954308

Cell therapy with human interleukin 10-producing ILC2s enhances islet function and inhibits allograft rejection. Colpitts SJ, Jegatheeswaran S, Oakie A, Mashhouri S, Sachewsky N, Murshed H, Mathews JA, Reid KT, Misra PS, Fung VCW, Reichman TW, Nostro MC, Verchere CB, Levings MK, Crome SQ.Am J Transplant. 2025 Sep;25(9):1858-1869. doi: 10.1016/j.ajt.2025.05.023. Epub 2025 May 23.PMID: 40412656 Free article.

Interleukin-4-mediated Pro-Regenerative Cellular Reprogramming in 3-dimensional Liver Culture. Camat D, Nakib D, Chung SW, Sekhon M, Liu Y, Lumanto P, Hyduk SJ, Perciani CT, Bartczak AM, Cheng ML, Pezzutti OI, Kaltagian M, Altaf F, Jafari SM, Manuel J, Thoeni C, Ogawa S, Ma XZ, McGilvray ID, MacParland SA.Cell Mol Gastroenterol Hepatol. 2025 Sep 2:101626. doi: 10.1016/j.jcmgh.2025.101626. Online ahead of print.PMID: 40907663 Free article.

Mesenchymal progenitor-derived proteoglycan 4 regulates the transdifferentiation of chondrocytes into osteoblasts during fracture healing. Ninkovic N, Corpuz JM, Stahl A, Olsen A, Unger CM, Ardebili AA, Sun H, Cha J, Kaketsis D, Manske SL, Haider IT, Marcucio RS, Schmidt TA, Jay GD, Underhill TM, Edwards WB, Rancourt DE, Biernaskie J, Krawetz RJ.Stem Cells Transl Med. 2025 Sep 11;14(9):szaf043. doi: 10.1093/stcltm/szaf043.PMID: 40973917 Free PMC article.

Prolonged length of stay in high-risk patients undergoing allogeneic stem cell transplantation: a call to action for addressing healthcare challenges. Sayyed A, Novitzky-Basso I, Remberger M, Clarke S, Chen C, Al-Shaibani E, Kim DDH, Viswabandya A, Kumar R, Lam W, Law AD, Gerbitz A, Pasic I, Michelis FV, Mattsson J.Bone Marrow Transplant. 2025 Sep;60(9):1236-1242. doi: 10.1038/s41409-025-02627-w. Epub 2025 Jun 3.PMID: 40461848

From β soloist to endocrine symphony: Subtype-complete islets conduct glucose harmony. Zhao J, Liang S, Kieffer TJ.Cell Stem Cell. 2025 Sep 4;32(9):1311-1313. doi: 10.1016/j.stem.2025.08.001.PMID: 40912231

Innate lymphoid cells in the spotlight: from biomarkers to blueprint for innovative immunotherapy. Kuo IC, Brassard J, Zandstra PW, McNagny KM.Front Immunol. 2025 Sep 2;16:1655730. doi: 10.3389/fimmu.2025.1655730. eCollection 2025.PMID: 40963622 Free PMC article. Review.

Generation of two human induced pluripotent stem cell lines from patient-derived fibroblasts with severe congenital defects of the vertebrae and neural tube. Lee JA, Conrad JV, Rusteika M, Drissi TH, Zhang T, Liu S, Singla S, Willetts L, Semper C, Rancourt D, Chu LF.Stem Cell Res. 2025 Sep 14;88:103837. doi: 10.1016/j.scr.2025.103837. Online ahead of print.PMID: 40997543 Free article.

Neuroregenerative and neuroprotective effects of bioengineered scaffolds in spinal cord injury: a systematic review of preclinical and early phase clinical studies. Khavandegar A, Safari Dehnavi N, Ganau M, Ramezani Z, Khodadoust E, Hassan Zadeh Tabatabaei MS, Maleki T, Mousavi MA, RayatSanati K, Esmaeili M, Eslami Nejad Parizi A, Hanna AS, Hassannejad Z, Fehlings MG, Sharif-Alhoseini M.Spinal Cord. 2025 Sep;63(9):451-469. doi: 10.1038/s41393-025-01114-9. Epub 2025 Aug 23.PMID: 40849360 Review.

Building the framework for bioprinted human heart tissue: recent developments and future prospects. da Silva VA, Leung MC, Clayton M, Oommen L, Madrigal H, Laksman Z, Yu B, Willerth SM.Regen Med. 2025 Sep;20(9):409-430. doi: 10.1080/17460751.2025.2558269. Epub 2025 Sep 11.PMID: 40932465 Review.

The next frontier in lung development and regeneration research: harnessing iPSC models to illuminate notch signaling pathways. Song Y, Yang S, Lam T, Quach HT, Yang J, Salih R, Wong AP.Front Cell Dev Biol. 2025 Sep 15;13:1672074. doi: 10.3389/fcell.2025.1672074. eCollection 2025.PMID: 41030635 Free PMC article. Review.

Ex Vivo Organ Perfusion Systems for Disease Modeling and Therapeutic Applications in Small Animal Models. Yeganeh M, Zito A, Sadat M, Pierro A, Rogers IM.J Tissue Eng Regen Med. 2025 Sep 18;2025:2583925. doi: 10.1155/term/2583925. eCollection 2025.PMID: 41018117 Free PMC article. Review.

SEPTEMBRE

Navigating challenges in human pluripotent stem cell-derived islet therapy for type 1 diabetes. Usama M, Deng Y, Chen Y, Milland T, Malleshaiah M, Aghazadeh Y. Front Immunol. 2025 Aug 4;16:1625439. doi: 10.3389/fimmu.2025.1625439. eCollection 2025.PMID: 40831568 Free PMC article. Review.

REST/NRSF Preserves muscle stem cell identity by repressing alternate cell fate. Sahinyan K, Blackburn DM, Simon MM, Lazure F, Kwan T, Wilson DH, Vahidyeganeh M, Alsadi N, von Maltzahn J, Yamada Y, Jahani-Asl A, Bourque G, Rudnicki MA, Soleimani VD. Nat Commun. 2025 Aug 12;16(1):7487. doi: 10.1038/s41467-025-62758-y.PMID: 40796549 Free PMC article.

Protocol for dual-optical mapping of voltage and calcium sensors in human pluripotent stem cell-derived cardiomyocytes. Alibhai FJ, Masoumi A, Kim HJ, Kim N, Kim W, Gomez-Garcia J, Lee P, Laflamme MA. STAR Protoc. 2025 Aug 23;6(3):104044. doi: 10.1016/j.xpro.2025.104044. Online ahead of print.PMID: 40849912 Free PMC article.

Human iPSCs-derived mesenchymal stem cells promote skin regeneration and burn wound healing. Farahat M, Brosset S, Chen Y, Aijaz A, Rix G, Challagundla B, Elloso M, Hutter MF, Rogers IM, Jeschke MG. NPJ Regen Med. 2025 Aug 30;10(1):40. doi: 10.1038/s41536-025-00427-w.PMID: 40885782 Free PMC article.

Modelling the liver’s regenerative capacity across different clinical conditions. Nguyen-Lefebvre AT, Ghosh S, Baciu C, Hasjim BJ, Naimimohasses S, Oldani G, Pasini E, Brudno M, Selzner N, Wrana J, Bhat M. JHEP Rep. 2025 May 30;7(8):101465. doi: 10.1016/j.jhepr.2025.101465. eCollection 2025 Aug. PMID: 40704068 Free PMC article.

 Satellite Cells in Regeneration and Disease. Esper ME, Saber J, Rudnicki MA. Cold Spring Harb Perspect Biol. 2025 Aug 18:a041474. doi: 10.1101/cshperspect.a041474. Online ahead of print. PMID: 40825664

Biosynthetic Collagen-Analog Hydrogels Stimulate Endogenous Regrowth of Rabbit Corneas: A Pilot Study. Timmerman I, Robert MC, Vergneau-Grosset C, Juette T, Benito J, Garbin M, Zamani-Roudbaraki M, Moradi M, Goodarzi H, Boutopoulos C, Benoit-Biancamano MO, Griffith M, Vanore M. Vet Sci. 2025 Aug 21;12(8):785. doi: 10.3390/vetsci12080785.PMID: 40872735 Free PMC article.

AI-Driven Quality Monitoring and Control in Stem Cell Cultures: A Comprehensive Review. Singh R, Orimi HE, Pedabaliyarasimhuni PKR, Hoesli CA, Chioua M. Biotechnol J. 2025 Aug;20(8):e70100. doi: 10.1002/biot.70100.PMID: 40785233 Free PMC article. Review.

Scientometric analysis of evolution in sex-specific MSC therapy for cardiovascular diseases. Verma E, Gupta M, Sierhuis R, Dhingra S. Biochim Biophys Acta Mol Basis Dis. 2025 Aug;1871(6):167878. doi: 10.1016/j.bbadis.2025.167878. Epub 2025 Apr 29. PMID: 40311883 Free article. Review.

A molecular systems architecture of the mesenchymal stromal cell microenvironment. Ayyadurai VAS, Deonikar P, Radhakrishnan V, Keating A. Stem Cells. 2025 Aug 22;43(9):sxaf042. doi: 10.1093/stmcls/sxaf042.PMID: 40843515 Free PMC article.

The Role of Mesenchymal Stromal Cells in the Treatment of Bronchopulmonary Dysplasia: A Multi-Prong Approach for a Heterogeneous Disease. Deguise MO, Thébaud B. Compr Physiol. 2025 Aug;15(4):e70038. doi: 10.1002/cph4.70038.PMID: 40853849 Free PMC article. Review.

Development of a tissue-specific bioscaffold for intestinal stem cell culture. Kakar S, Derouet MF, Zhang L, Gillis CJ, Larsen F, Paul A, Flynn LE, Asfaha S. PLoS One. 2025 Aug 6;20(8):e0328898. doi: 10.1371/journal.pone.0328898. eCollection 2025.PMID: 40768435 Free PMC article.

In silico modeling of directed differentiation of induced pluripotent stem cells to definitive endoderm. Mostofinejad A, Romero DA, Brinson D, Waddell TK, Karoubi G, Amon CH. PLoS Comput Biol. 2025 Aug 21;21(8):e1013407. doi: 10.1371/journal.pcbi.1013407. Online ahead of print.PMID: 40839670 Free article.

Micropocket-Based Differentiation System to Streamline and Scale Stem Cell-Derived Pancreatic Islet Production. O’Brien S, Li C, Trana R, Hoesli C, Moraes C. ACS Biomater Sci Eng. 2025 Aug 11;11(8):5096-5106. doi: 10.1021/acsbiomaterials.5c00372. Epub 2025 Jul 23.PMID: 40700651

Tissue Engineering Nasal Cartilage Grafts with Three-Dimensional Printing: A Comprehensive Review. Perry AC, Adesida AB. Tissue Eng Part B Rev. 2025 Aug;31(4):331-356. doi: 10.1089/ten.TEB.2024.0187. Epub 2024 Oct 22.PMID: 39311456 Review.